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โ† Trials
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Influences of Propofol and Sevoflurane Anesthesia in Ovarian Cancer (Anesthetics)

RecruitingPhase 4Ages 20 Years - 80 YearsFemaleKaohsiung Medical University Chung-Ho Memorial Hoโ€ฆ
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In plain words

What the trial is, and whether it could suit you

โ…ฆ. Study procedures (summary) 1. Written informed consent must be obtained before any study specific procedures are undertaken. Qualified participants were identified at the pre-anesthesia evaluation clinic or ward. The informed consents are obtained from the patient in the ward at night before the operation. 2. The process of the experiment (brief describe) In the preoperative waiting area, the patients are randomly assigned and divided into two groups according to the allocation sequence table (corresponding to 1:1 randomization) generated by the computer. The propofol group was both induced and maintained at an effect-site concentration (Ce) of 2.0-4.0 mcg/mL by a target-controlled infusion (TCI) system. The sevoflurane group was maintained via sevoflurane vaporizer between 1% and 3% (target minimum alveolar concentration of 0.7-1.3). During the operation, the dose of anesthetic

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Twenty to eighty-year-old. 2. ASA class I-III. 3. Patients undergoing elective craniotomy for primary ovarian tumors under general anesthesia. Exclusion Criteria: 1. Severe mental disorder 2. Poor liver function 3. Pregnant or lactating women 4. Morbid obesity 5. Have a history of allergy to any drug used in this study 6. Non-primary ovarian cancer surgery 7. Undergoing ovarian cancer pathological section surgery 8. Patients with incomplete medical records 9. Combined with other surgeries, emergency surgeries 10. Concomitant patients with other non-ovarian cancer therapy 11. Patients receiving palliative treatment after ovarian cancer surgery 12. During the maintenance period of anesthesia, propofol or sevoflurane should not be used as anesthetic drugs 13. Intraoperative combined use of multiple anesthetics (such as ketamine, dexmedetomidine, other inhalation anesthetics) 14. Those diagnosed with benign tumors before and after surgery 15. Patients with metastases to the ovary
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What it tests

  • Propofol 1%
  • Sevoflurane/Ultane
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Where

1 site
Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung City, Taiwan
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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