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Electrical Impedance Tomography for Identification of Optimal Positive End-expiratory Pressure in Newborn Infants

Recruitingn/aAges 0 Days - 28 DaysAllUniversity Children's Hospital Basel
NCT05612256 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Electrical impedance tomography (EIT) enables assessment of regional lung ventilation at the bedside. EIT has been safely used in newborn infants to image intrathoracic lung volume patterns as early as from the first minute of life. This prospective single-centre observational study is to identify optimal PEEP in infants on respiratory support by measurements of EIT, FOT and SOPI.

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📋 Eligibility rules (as published)
Inclusion Criteria: * 22+0 to 41+6 weeks' gestational age * Requiring mechanical ventilation * Written informed parental consent Exclusion Criteria: * Major congenital malformations including lung and cardiac malformations * Infants on high frequency oscillatory ventilation * Lack of written informed parental consent
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What it tests

  • Electrical impedance tomography (EIT)
  • Forced oscillation technique (FOT)
  • Saturation oxygenation pressure index (SOPI)
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Where

1 site
Department of Neonatology, University Children's Hospital Basel UKBB
Basel, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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