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Clinical and Biological Aspects of the MONKEYPOX Disease

RecruitingNAAges 18 Years - anyAllInstitut Pasteur
NCT05627713 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Monkey pox virus (MPXV), of the genus Orthopoxvirus, regularly causes epidemics in endemic areas of central and western Africa. Since January 1, 2022, cases of Monkey pox have been reported to WHO by 96 Member States in the 6 WHO regions. As of 22 August 2022, a total of 41,664 laboratory-confirmed cases and 192 probable cases, including 12 deaths, have been reported to WHO. Since May 13, 2022, a high proportion of these cases have been reported from countries where monkey pox transmission had not previously been documented. For the first time, cases and sustained chains of transmission are being reported in countries without direct or immediate epidemiological links to areas in West or Central Africa (WHO 2022). France is one of the most affected countries with 2889 cases reported as of August 22, 2022. This situation led the WHO Director General to declare, on July 23, 2022, that the

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult, * eligible for MPXV vaccination according to HAS criteria or suspected of MPXV infection * whose health status is compatible with a 45 ml single blood sample * who have consented to participate in the study * who are covered by a Social Health Insurance plan Exclusion Criteria: * Person with MPXV vaccination without proof of vaccination. * For persons presenting for MPXV vaccination: presence of a contraindication to vaccination other than a current infection. * Pregnant and lactating women * Person unable to give informed consent to participate
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What it tests

  • Blood sample collection
  • urine sample collection
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Where

1 site
Centre Médical de l'Institut Pasteur
Paris, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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