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The Effect of Eyeliner on Tear Composition, Tear Secretion and Tear Film Stability.

Recruitingn/aAges 20 Years - 35 YearsFemaleZhongnan Hospital
NCT05632887 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Eyeliner is one of the most common eye cosmetics. The main ingredients are titanium oxide, pigment, grease and preservative. The user will apply the eyeliner to the eyelid and eyelash. With the blinking again and again, the components of the eyeliner may enter the tear film and continue to act on the eye surface. Therefore, the investigators suspect that the use of eyeliner may be an important factor leading to dry eye disease. In order to explore the relationship between the use of eyeliner and dry eye disease, the investigators plan to collect eye surface characteristic data of the two groups of people who use eyeliner and who do not use it.Then use Raman analysis to explore whether the use of eyeliner will lead to changes in tear composition.The investigators intend to analyze the difference of tear composition between the two groups to understand the relationship between the change o

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📋 Eligibility rules (as published)
Inclusion Criteria: * People aged 20-35 who use eyeliner or do not use eyeliner . * People who use eyeliner have used it for ≥ 1 year; Frequency ≥ 3 times/week. Exclusion Criteria: * Other serious systemic diseases. * Other systemic diseases related to ocular surface, such as rheumatoid arthritis, systemic lupus erythematosus, Sjogren's syndrome and other immune system diseases or other eye diseases, history of eye surgery and trauma. * Lactating women or pregnant women. * Use electronic products for more than 4 hours every day. * Patients with circadian rhythm disorder. * People with radiation exposure history. * Non permanent residents in Wuhan.
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What it tests

  • no intervention
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Where

1 site
Zhongnan Hospital of Wuhan University
Wuhan, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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