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Contrast-Enhanced Ultrasound Imaging for Diagnosing Recurrent Renal Cell Carcinoma (RCC) Post Ablation

RecruitingPhase 2Ages 18 Years - anyAlljohn eisenbrey
NCT05641935 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This phase II trial studies how well contrast-enhanced ultrasound (CEUS) works for diagnosing patients with renal cell cancer (RCC) that has come back (recurrent) after an ablation. Diagnostic imaging, such as CEUS, may help find and monitor long term renal cell cancer recurrence following cryo or microwave ablation.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Previously received cryotherapy or microwave therapy of RCC * Has available contrast enhanced (CE)-MRI or CE-CT imaging prior to ablative therapy * Have previously had or are scheduled to have a contrast-enhanced MRI/CT for the monitoring of RCC recurrence within 4 weeks of the CEUS study * Be at least 18 years of age * Be medically stable * If a female of child-bearing age, must have a negative pregnancy test * Have signed Informed Consent to participate in the study Exclusion Criteria: * Patients who are medically unstable, patients who are seriously or terminally ill, and patients whose clinical course is unpredictable * Patients with known sensitivities to the components of Lumason
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What it tests

  • Sulfur Hexafluoride Lipid Microspheres
  • Contrast-Enhanced Ultrasound
  • Computed Tomography
  • Magnetic Resonance Imaging
  • Electronic Health Record Review
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Where

1 site
Sidney Kimmel Cancer Center at Thomas Jefferson University
Philadelphia, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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