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Exercise to Improve Sleep in Parkinson's Disease

RecruitingNAAges 40 Years - anyAllMcGill University
NCT05644327 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study will investigate the impact of three common exercise modalities, cardiovascular, resistance, and multimodal (i.e., a combination of the previous two) training, on sleep quality and architecture in persons with Parkinson's disease (PD). Furthermore, the project will investigate whether the potential positive exercise-induced changes in sleep are associated with improvements in different quality of life (QoL)-related aspects. Participants will perform either cardiovascular training (CT), resistance training (RT), multimodal training (MT), or will be allocated to a control condition (i.e., waiting list - CON) for 12 weeks. Training will be performed three times/week. The assessments will be conducted at baseline, post-intervention, and follow-up (i.e. 8 weeks after the intervention) by assessors blinded to the participants' group allocation.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Persons with mild-moderate idiopathic Parkinson's Disease (Modified Hoehn \& Yahr Scale stages 0.5-3.5); * On a stable dosage of medication during the previous month; * Having poor sleep quality defined as a score \> 15 in the PDSS-2 and/or reporting subjective sleep complaints affecting their sleep quality; Exclusion Criteria: * Having atypical parkinsonism, dementia, stroke, or any other neurological condition; * Presenting severe untreated obstructive sleep apnea (OSA); * Having a Montreal Cognitive Assessment (MoCA) score \<18 * Having a Beck Depression Inventory score \>31; * Having absolute contraindications to exercise; * Having severe osteoporosis; * Participating in an exercise or drug trial during the period of the study; * Exceeding the physical activity levels recommended for the general population (≥150 minutes/week of moderate-intensity or ≥75 minutes/week of vigorous-intensity cardiovascular activity) and/or strengthening activities ≥2 days/week.
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What it tests

  • Cardiovascular training (CT)
  • Resistance training (RT)
  • Multimodal training (MT)
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Where

3 sites
Jewish Rehabilitation Hospital
Laval, Canada
Human Brain Control of Locomotion Laboratory
Montreal, Canada
Cummings Centre
Montreal, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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