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CATCH: Implementation of Genomics-guided Precision Medicine in Metastatic Breast Cancer

Recruitingn/aAges 14 Years - 100 YearsAllGerman Cancer Research Center
NCT05652569 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

CATCH is an indication-specific diagnostic platform, which drives the implementation of integrative, genomic profiling for metastatic breast cancer into the clinics. The main objective of this approach is to identify biomarkers and drug targets to guide targeted therapeutic interventions. Eligible are all metastatic breast cancer patients (independent of gender), irrespective of molecular subtype. At initial diagnosis of distant metastasis or progress at disease progression, biopsy samples from a prognostic-relevant metastasis are retrieved during standard-of-care procedures for central analyses, together with blood samples. In parallel to all standard-diagnostic measures, genomic and transcriptomic profiling is conducted to infer the underlying biology of the disease and identify patients who might profit from biomarker-guided interventions in clinical trials. Samples not required fo

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📋 Eligibility rules (as published)
Inclusion Criteria: * Female and male breast cancer patients ≥ 18 or if the legal guardian has agreed to the respective informed consent form (ICF) * Patients with advanced or metastatic breast cancer (irrespective of clinical parameters such as TNM, subgroups, therapy lines) * Patients, who agreed to and were able to sign the informed consent form. Exclusion Criteria: * Early breast cancer * Inability to take a tissue bioptic sample due to reasons such as physical location of the lesion or health of the patient * Any physical or mental handicap or severe comorbidities that would hamper the adequate cooperation with the patient.
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What it tests

  • Genomic Profiling / Sequencing
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Where

12 sites
University Hospital Augsburg
Augsburg, Germany
Charité
Berlin, Germany
University Hospital Köln
Cologne, Germany
Medical Faculty and University Hospital Carl Gustav Carus
Dresden, Germany
University Hospital Erlangen
Erlangen, Germany
University Hospital Essen
Essen, Germany
National Center for Tumor Diseases
Heidelberg, Germany
Caritas Hospital St. Josef
Regensburg, Germany

…and 4 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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