Effects of Increasing Mean Arterial Pressure on Renal Function in Patients With Shock and With Elevated Central Venous Pressure

Inclusion Criteria: * Adult patients (≥ 18 years old ) * Arterial hypotension requiring the etablishment of catecholamines * Norepinephrine dose ⩾ 0.1µg/kg/min at the inclusion * High central venous pressure ≥ 12mmHg * Cardiac output monitoring (PICCO or Swan Ganz) Exclusion Criteria: * Anuria * Patient with an emergency indication of renal replacement therapy (severe hyperkalemia, severe metabolical acidosis with pH \<7.15, acute pulmonary edema due to fluid overload resulting in severe hypoxemia, serum urea concentration \> 40 mmol/l) * Pregnant, lactating or parturient woman * Patient deprived of liberty by judicial or administrative decision * Patient with psychiatric compulsory care * Patient subject to legal protection measures * Patients with do-no-reanimate order or withdrawal of life sustaining support