AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

This is a Study to Evaluate Nanofractures Technique in the Treatment of Cartilage Lesions

RecruitingNAAges 16 Years - 50 YearsAllEnte Ospedaliero Cantonale, Bellinzona
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

Articular cartilage lesions, with their inherent limited healing potential, remain a challenging problem for orthopaedic surgeons. Various techniques, both palliative and reparative, have been used to treat this injury with variable success rates. If not adequately treated, they may even lead to the development of early-onset osteoarthritis. Among all the available techniques, microfractures are used in restoring the cartilage tissue, especially in the deep and extended lesions. More recently, the need for minor bone trauma with still adequate bleeding resulted in the development of nanofractures. Nanofracturing means creating perforations with a smaller diameter that go deeper into the bone while damaging it less. This is supposed to reduce the injury to the subchondral bone and increase the amount of bone marrow-derived mesenchymal stromal cells at the bone surface. Thus, the aim of

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Patients with cartilage lesions of the knee scheduled for surgery * Age 16-50 * BMI between 18.5 and 30 points * Ability to give informed consent Exclusion Criteria: * Uncorrected knee instability * Meniscectomy \> 50% * Uncorrected knee misalignment * Uncontrolled metabolic diseases * Inability to give informed consent
๐Ÿ’Š

What it tests

  • Nanofracture
๐Ÿ“

Where

1 site
EOC
Lugano, Switzerland
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy