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Study of the Aortic and Large Arterial Vessel Infections

Recruitingn/aAges 18 Years - anyAllCentral Hospital, Nancy, France
NCT05660733 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Aortic or large arterial vessel infections are rare but serious infections. Their management is based on French and American expert opinions. The quality of evidence supporting these guidelines is low because most publications on the subject correspond to case series and few interventional studies have been performed to validate their management. However, referral centres for vascular surgery are frequently solicited to give their opinion on patients suffering from mycotic aneurysms. In addition, the last few decades have seen the improvement of vascular surgery techniques allowing the management of more and more patients, often elderly and comorbid. There has therefore been an increase in the incidence of infectious complications associated with this care. It is therefore essential to participate in research on aortic and large arterial vessel infections. For this, a monocentric cohort

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years * Aortic or large arterial vessel infection. The diagnosis is made on a number of criteria in favour of the diagnosis (at least 2 of the following 3 criteria): * Compatible clinical presentation: local or general inflammatory signs suggestive of a deep infection (fever, chills, scar discharge, fistula, febrile abdominal pain and low back pain, ...) or per-operative finding of an infection in contact with native or prosthetic vascular tissue * And/or biological (inflammatory syndrome) and/or imaging evidence (infectious sign on native, bioprosthetic or prosthetic vascular tissue on CT and/or PET scan) in favour of the diagnosis * And/or microbiological evidence (positive serologies, blood cultures or deep samples in favour of infection) Exclusion Criteria: * Patient who objected to participation in this protocol and data collection * Pregnant woman, parturient or breastfeeding mother * Person deprived of liberty by a judicial or administrative decision, * Person subject to psychiatric care by virtue of articles L.3212-1 and L.3213-1 of the French public health code * Person subject to a legal protection measure * Person unable to give consent
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What it tests

  • Not listed
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Where

1 site
Université de Lorraine, CHRU Nancy and APEMAC
Vandœuvre-lès-Nancy, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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