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Using Transcranial Alternating Current Stimulation to Improve Executive Function in 22q11.2 Deletion Syndrome

RecruitingNAAges 14 Years - 25 YearsAllStephan Eliez
NCT05664412 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this project is to explore the effects of transcranial alternating current stimulation (tACS) in children, adolescents and young adults with a 22q11.2 microdeletion. The main aim of the present research project is to investigate the effects of repeated, individually tuned high-density (HD) tACS on cognition (i.e., WM performance) and related neuroimaging markers in carriers of the 22q11DS. As cognitive deficits, most notably WM impairment, are among the earliest signs of psychotic disorders, interventions during adolescence aimed at reducing cognitive decline in at-risk individuals may prove effective in delaying or even preventing the later emergence of psychotic symptoms.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Confirmed genetic diagnosis of 22q11DS * Age between 14 and 25 years old * Willingness to participate * Informed Consent signed by the subject and/or the caregiver(s) Exclusion Criteria: * Epilepsy * Deep brain stimulation electrodes * Traumatic brain injury * Facial metal implants
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What it tests

  • at-home tACS using Starstim-Home tES
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Where

1 site
University of Geneva
Geneva, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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