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โ† Trials
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Laryngeal Cryotherapy for Refractory Neurogenic Cough

Recruitingn/aAges 18 Years - anyAllUniversity of Texas Southwestern Medical Center
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In plain words

What the trial is, and whether it could suit you

This study aims to evaluate the safety and efficacy of upper aerodigestive tract cryotherapy treatment in patients with refractory neurogenic cough in a prospective pilot study with a validated patient reported outcome measure

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Adult patients 18 years or older with diagnosis of neurogenic cough * Neurogenic cough is a diagnosis of exclusion applied to persistent cough (8 weeks or longer) * Negative workup for other causes, including sinonasal allergies/chronic sinusitis, cough-variant asthma, and GERD * Patient willing to participate in a clinical trial Exclusion Criteria: * Uncontrolled reflux (scoring on Reflux Symptom index of 13 or higher) * Vocal fold abnormalities or impairment * History of asthma or other underlying lung condition not adequately treated or controlled * Uncontrolled Allergic Rhinitis (Total Nasal Symptom Score \>6, which would indicate moderate disease32) * Reported symptom of postnasal drip * Current smoker * Current neuromodulator medication use * Patient unwilling to participate in clinical trial or sign an informed consent * End stage medical disease with poor life expectancy * Medical instability deemed by the investigators as a contraindication for enrollment * Abnormal Chest X-ray * Abnormal pulmonary function testing (PFTs) * Positive local allergy panel (combined RAST testing)
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What it tests

  • Laryngeal cryotherapy
  • Cryoprobe
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Where

1 site
UT Southwestern Medical Center
Dallas, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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