🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Coagulation in Cirrhosis

RecruitingPhase 4Ages 18 Years - anyAllMedical University of Vienna
NCT05667805 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Out of fear of bleeding, liver cirrhosis patients are often treated prophylactically with blood and coagulation products before minor interventions. The COUCH study will examine whether these patients benefit from a restrictive administration of coagulation products.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: Patients at the University Hospital of Vienna with diagnosed liver cirrhosis and deranged coagulation parameters (INR \>1,5 AND/ OR platelet count \<50 G/L) who are scheduled for one of the following elective invasive interventions of the liver * Biopsy or puncture * Microwave ablation (MWA) or radiofrequency ablation (RFA) * Transjugular intrahepatic portosystemic shunt (TIPS) * Percutaneous transhepatic cholangiography drain (PTCD) Exclusion Criteria: * Missing informed consent or inability to consent * Age \< 18 years * Pregnancy or breastfeeding * Manifest ascites * Chronic kidney injury stage G4 or G5, KDIGO * Uninterrupted anticoagulant therapy, except for acetylsalicylic acid (ASA) * History of bleeding or clinical signs of a hemorrhagic diathesis in the physical examination (e.g., petechia, ecchymosis, mucosal bleeding, hemorrhagic diathesis within the family, menorrhagia, prolonged bleeding after surgery)
💊

What it tests

  • Platelet Concentrate
  • Prothrombin Complex Concentrate
  • Restricitve Use
📍

Where

1 site
General Hospital of the Medical University of Vienna
Vienna, Austria
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy