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Sonographic Diaphragm Function in AECOPD

Recruitingn/aAges 18 Years - anyAllIsala
NCT05671198 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The study will be conducted as a single-center, prospective cohort study. The primary objective of this study is to investigate the responsiveness of sonographic parameters of diaphragm to detect change in Borg score for dyspnea during hospitalisation for AECOPD without respiratory acidosis.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Hospitalisation primarily because of severe acute exacerbation of COPD * COPD, according to GOLD 2018 definition * Post-bronchodilator FEV1/FVC \< 0,70 and FEV1% \< 80%pred. within last 5 years Exclusion Criteria: * Respiratory acidosis (pH \< 7.35 ánd PaCO2 \> 6 kPA) * Need for (non-)invasive ventilation based on other criteria (e.g. severe hypoxia) upon presentation. * Established diagnosis of diaphragm diaphragm paralysis. * Inability for diaphragm imaging (e.g. mechanical ventilation, or unable to follow vocal instructions). * Those not able or unwilling to give written informed consent. * Pregnant women
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What it tests

  • Ultrasound of the diaphragm
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Where

1 site
Isala Klinieken
Zwolle, Netherlands
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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