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Usefulness of PET-CT for Invasive Fungal Infection

Recruitingn/aAges 18 Years - anyAllPuerta de Hierro University Hospital
NCT05688592 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this national multicenter prospective cohort study is to learn about the added value of 18F-FDG (18F-2-fluoro-2-deoxy-D-glucose) PET-CT in invasive fungal disease management. The main questions it aims to answer are: 1. Does the use of 18F-FDG PET-CT allow a better characterization of invasive fungal infection (IFI) (performance) compared to the exclusive use of conventional radiological studies in terms of extension/staging and monitoring of response/follow-up ? 2. Does the systematic and protocolized use of 18F-FDG PET-CT in IFI allow a better management of patients with IFI and increase the prognostic value of the initial evaluation? Participants will undergo systematically a 18F-FDG PET-CT as part of the work-up of their invasive fungal disease. Researchers will compare the performance of 18F-FDG PET-CT with standard management without 18F-FDG PET-CT to see if adds value

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📋 Eligibility rules (as published)
Inclusion criteria: * 18-year-old adult patients * who are admitted with a diagnosis of invasive fungal infection * who able to undergo a one 18F-FDG PET-CT * who give their informed consent. Exclusion criteria: * concomitant active bacterial infection likely to produce uptake in organs and tissues * recent surgery in the area of the IFI (in the previous 3 months) * other medical conditions that interfere with the development of the study ( e.g., inability to tolerate the performance of the test during the required time, pregnancy) * terminal situation.
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What it tests

  • PET-CT
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Where

14 sites
Hospital Universitario Puerta de Hierro
Majadahonda, Spain
Hospital de Bellvitge
Barcelona, Spain
Hospital Universitario Clinic
Barcelona, Spain
Hospital Universitario Virgen de las Nieves
Granada, Spain
Hospital Infanta Leonor Hospital
Madrid, Spain
Hospital Universitario Gregorio Marañón
Madrid, Spain
Hospital Universitario La Paz
Madrid, Spain
Hospital Unversitario Ramón y Cajal
Madrid, Spain

…and 6 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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