AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Evaluation of Superior Rectal Arterial Embolization in Hemorrhoidal Disease

RecruitingNAAges 18 Years - anyAllUniversitair Ziekenhuis Brussel
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

SRAE is a promising treatment of bleeding HD as a minimally invasive approach without sphincter damage nor direct mucosal anorectal trauma. Feasibility, efficacy and safety were studied in several trials. A randomized controlled study should confirm the benefits of this technique and will define its therapeutic role in HD. Embolization and DG-HAL are based on the same concept of vascular occlusion of hemorrhoidal branches of the rectal artery. Furthermore, DG-HAL and RBL are equally effective procedures. The assumption is that treatment with SRAE is not inferior in comparison to RBL or DG HAL in respectively patients without or with antiplatelet/anticoagulation therapy in terms of symptom control and bleeding (non-inferiority study).

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * All patients referred for Hemorrhoidal disease with bleeding are eligible. Significant bleeding is defined as a HBS of โ‰ฅ 5. * Age \> 18 years old; * Sexes eligible for study: all * Hemorrhoidal disease grade I-III according the Goligher classification with rectal bleeding as predominant symptom * History of prior instrumental treatment of HD does not prohibit inclusion * Able to understand and read Dutch, French or English Exclusion Criteria: * Permanent hemorrhoidal prolapse/grade IV hemorrhoidal disease * Rectal prolapse * History of proctological surgery for HD * Acute complicated course of HD i.e. acute thrombosis (fluxio hemorrhoidalis or perianal hematoma) * Anal stenosis, congenital of acquired * Chronic anal fissure * Active rectal inflammation, including peri-anal abscess (e.g. Inflammatory Bowel Disease, infectious,โ€ฆ) * History of colorectal or anal cancer * History of rectal or sigmoidal resection * Portal hypertension and liver cirrhosis Child Pugh C * Radiation rectitis * Neurological disease involving anal sphincter musculature * Severe psychiatric disorder * Pregnancy * Allergy to iodinated contrast agents * Colorectal neoplasia as the cause of bleeding (excluded with a (virtual) colonoscopy in the last year)
๐Ÿ’Š

What it tests

  • Rubber band ligatures (RBL)
  • Superior Rectal Artery Embolization (SRAE)
  • Doppler-Guided Hemorrhoidal Artery Ligation (DG-HAL)
๐Ÿ“

Where

1 site
UZ Brussel
Jette, Belgium
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy