MRS of Glioma Genomics

Inclusion Criteria : * Affiliations to a social security scheme (as a beneficiary or a person entitled to benefits) * Obtainig written, informed consent * One of the following two situations * Group 1 : Probable grade II/III/IV glioma, for which excision is scheduled. * Group 2 : Histologically confirmed grade II or III glioma with known IDH1/IDH2 status, which has received no treatment other than surgery and is due to undergo therapy other than surgery. * Presence of measurable tumor residue (\>2 cm in diameter on FLAIR imaging) * Karnofsky Index \> 60 * Effective contraception throughout the study, supplemented by a negative pregnancy test for women of childbearing age. Exclusion Criteria: • Containdications to MRI : Pacemaker or neural stimulators, intraocular or intracerebral metallic foreign bodies, cochlear implant, heart valve or metallic surgical arterial devices that are not MRI ompatible, metallic devices susceptible to concentrating radio-frequency pulses, claustrophobia * Pregnant or breastfeeding women * Regulatory criteria : Pregnant women, women in labor, breastfeeding women ; Failure to sign the consent form or paticipant refusal ; Legal protection measures (guardianship, curatorship, judicial protection) ; Participation in another research study that does not allow for compliance with the exclusion period between the two studies ; Individuals not covered by a health insurance scheme.