๐ฌIn plain words
What the trial is, and whether it could suit you
The main purpose of this study is to determine whether differences in myocardial reserve predict clinical outcomes for heart failure patients.
Sign in to get the eligibility rules as simple questions to take to your doctor.
๐ Eligibility rules (as published)
Inclusion Criteria:
1. LVEF โค 40%
2. Referred for RHC for:
1. Evaluation for advanced heart failure therapies, including LVAD, OHT, temporary or long-term inotrope therapy, or counter-pulsation (temporary or long-term with NuPulse device OR
2. Accurate assessment of invasive hemodynamics due to worsening clinical status, OR
3. Assessment of myocardial recovery for consideration of LVAD or counter-pulsation (temporary IABP or long-term with NuPulse device) decommissioning or removal OR
4. Assessment of cardiac function and valvular abnormalities prior to planned valvular surgery for MR or AI
3. Estimated glomerular filtration rate (eGFR) โฅ 30 ml/min/1.73 m2
4. Age โฅ 18 years-old
5. Intent for admission based on RHC data
Exclusion Criteria:
1. eGFR \< 30 ml/min/1.73 m2
2. Severe, non-revascularized coronary artery disease
3. Concurrent acute coronary syndrome
4. Age \< 18 years-old
5. History of significant ventricular arrhythmia without an ICD
๐
What it tests
- 1:1 Randomization to receive milrinone
The University of Chicago
Chicago, United States
๐ค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ always decide together with your own doctor.