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Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift

RecruitingEARLY Phase 1Ages 18 Years - anyAllUniversity of Virginia
NCT05701969 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Anesthesiology residency requires extended and overnight shifts, which may negatively impact the quantity and quality of sleep. Previous studies have investigated the effect of night float shift work on anesthesiology resident sleep and performance and demonstrated that total sleep quantity and time spent in deep and rapid eye movement (REM) sleep were significantly reduced during night float and did not return to baseline after 3 nights of recovery. Melatonin is a hormone produced by the pineal gland, which regulates the circadian rhythm that governs sleep. Exogenous melatonin may be used as a sleep aid and is available over the counter in the United States. Melatonin is effective in realigning the circadian rhythm disorder caused by night shift work and increasing sleep duration; however, melatonin's effect on improving sleep in resident trainees has not been investigated. The invest

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📋 Eligibility rules (as published)
Inclusion Criteria: * Post-Graduate Year 1-5 * Current enrollment in anesthesiology, general surgery, obstetrics and gynecology, general medicine, or pediatrics residency at the Unversity of Virginia Exclusion Criteria: * Current use of sleep aids * Diagnosed sleep disorder * History of a pacemaker or other medical device. * pregnant or breast-feeding females * Bleeding disorders * Depression * High blood pressure * Seizure disorders * History of transplant on immunosuppression therapy.
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What it tests

  • Melatonin
  • Placebo
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Where

1 site
University of Virginia
Charlottesville, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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