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Healthy Mums, Healthy Babies: Multiple Micronutrient Supplementation in Ethiopia

Recruitingn/aAges 15 Years - 49 YearsFemaleLondon School of Hygiene and Tropical Medicine
NCT05708183 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Background: This programme effectiveness study responds to the need for evidence on the effect on birthweight of switching from iron-folic acid supplementation (IFA) to multiple micronutrient supplementation (MMS) as part of routine antenatal care in Ethiopia. A 2019 meta-analysis of trial data reported a mean improvement of 35g in newborn birthweight amongst newborns born to women who took MMS in pregnancy compared to those who took IFA. Responding to this evidence, in 2020 the World Health Organisation updated its global guideline on MMS from 'not recommended' to 'recommended in the context of rigorous research'. The guideline identifies priority research being 'to establish the impact of switching routine antenatal IFA to MMS on important health outcomes, equity, acceptability, feasibility, sustainability and health-care resources in different country settings.' In 2022 the Ministry o

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📋 Eligibility rules (as published)
Inclusion Criteria: * For the primary outcome, mothers who deliver a liveborn child in enrolled health facilities and who are willing/consent to participate in the study. * For the secondary objectives, all antenatal care staff and women attending for routine antenatal care during the survey periods will be included. Exclusion Criteria: * For the primary outcome, stillbirths will be excluded. Data for any newborn who subsequently dies while still in the facility will be excluded from all secondary analyses.
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What it tests

  • Multiple micronutrient supplementation (MMS)
  • Iron folate supplementation (IFA)
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Where

6 sites
Gambella
Ītang, Ethiopia
Oromia
Gīmbīcho, Ethiopia
Sidama
Bona Gena, Ethiopia
SNNPR
Dara, Ethiopia
Somali
Āwarē, Ethiopia
Ethiopia Public Health Institute
Addis Ababa, Ethiopia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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