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Effect of Combined Endurance Training on ADL and Walking in COPD Patients

RecruitingNAAges any - anyAllIstituti Clinici Scientifici Maugeri SpA
NCT05708443 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Chronic Obstructive Pulmonary Disease (COPD) is a chronic disease with related exercise intolerance and marked disability due to symptoms such as dyspnea and fatigue. Effort intolerance and exercise-induced symptoms cause marked impairment in completing activities of daily living (ADL). Pulmonary rehabilitation (PR), which has exercise as a major component, is considered a key treatment in the management of COPD since PR is effective in improving exercise tolerance, exercise-induced dyspnea and fatigue, and health-related quality of life. Rehabilitation is also effective in improving the time required to perform ADLs, reducing symptoms and disability. Studies show that rehabilitation protocols with upper limb exercises added to lower limb training are able to give additional benefits in terms of effort tolerance (endurance time at the arm ergometer and oxygen consumption) and reduction o

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📋 Eligibility rules (as published)
Inclusion Criteria: * GOLD class 2-3 COPD * Forced Expiratory Volume in the first second (FEV1) between 30% and 70% of the predicted value * ability to walk and climb stairs without assistance * stable clinical condition (pH \> 7.35) Exclusion Criteria: * chronic respiratory insufficiency on long-term oxygen therapy (LTOT) * severe orthopedic, neurological or cardiological comorbidities * cognitive impairment * recent exacerbation (within 15 days) requiring a change in therapy * presence of lung disease other than COPD * terminality
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What it tests

  • LL group
  • L+UL group
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Where

3 sites
ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Lumezzane
Lumezzane, Italy
ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Montescano
Montescano, Italy
ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Tradate
Tradate, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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