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CMV Immunity Monitoring in Lung Transplant Recipients

RecruitingPhase 2Ages 18 Years - 99 YearsAllNYU Langone Health
NCT05708755 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to determine the safety and feasibility of using a laboratory test to guide duration of antiviral prophylaxis with valganciclovir (medication used to prevent viral infections) after lung transplant. The laboratory test, inSIGHT™ CMV T Cell Immunity Panel, measures patients' immune response to a common viral infection known as cytomegalovirus (CMV). The goal of this study will be to safely decrease how long patients need to take valganciclovir based on the results of the CMV T Cell Immunity Panel.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Received a lung transplant, or multi-organ transplant involving a lung at NYU Langone Health 2. Pre-existing serological immunity to CMV (R+) 3. Able and willing to provide informed consent Exclusion Criteria: 1. Anti-thymocyte globulin induction immunosuppression 2. Perioperative desensitization 3. Pregnant or breastfeeding women
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What it tests

  • Cytomegalovirus T Cell Immunity Panel (CMV-TCIP)
  • Donor-Derived Cell-Free DNA (dd-cfDNA) Assay
  • Valganciclovir
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Where

1 site
NYU Langone Health
New York, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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