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UPURS Trial for Patient-centered Management of Symptomatic Obstructing Stones

RecruitingNAAges 18 Years - anyAllUniversity of California, San Francisco
NCT05715086 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

A prospective, non-blinded, randomized controlled trial studying the management of symptomatic ureteral stones. This study will compare upfront ureteroscopy vs observation and delayed intervention for patients presenting to the emergency department with a symptomatic ureteral stone.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Presenting to the Emergency Department (ED) * Adult (\> 18 yo) * ≥5mm ureteral stone diagnosed on CT scan * Presence of symptoms (pain, nausea, vomiting, hematuria) Exclusion Criteria: * Strict indication for stent * Stone burden not amenable to Ureteroscopy (URS) * Dirty urine analysis (UA) or positive urine culture (UCx) * Transplant kidney * Presence of conduit * Comorbidities not optimized for surgery * Strong preference for surgery or observation
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What it tests

  • Ureteroscopy
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Where

2 sites
University of California, San Francisco
San Francisco, United States
University of Colorado
Aurora, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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