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Aortic Stiffness in Patients With Genetic Aortopathies

Recruitingn/aAges any - anyAllIRCCS Policlinico S. Donato
NCT05715203 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to study arterial stiffness in patients with thoracic ascending aortic aneurysms (TAA), either syndromic or non-syndromic. The main questions it aims to answer are: * Stratification of aortic risk based on arterial stiffness; Compare measurements with morphological and haemodynamic features of the ascending thoracic aorta. Participants will be asked to undergo non-invasive evaluation of blood pressure and arterial stiffness.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Subjects with AAT, either syndromic or non syndromic; * Signed informed consent Exclusion Criteria: * Patients with early menopause and/or osteoporosis, rheumatic heart disease and active malignant tumours; * Patients with acute and chronic inflammatory conditions such as: chronic liver disease, chronic renal insufficiency and diseases affecting the thyroid system; * Seropositivity to HIV, HCV, HBsAg and SARS-CoV-2; * Pregnancy
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What it tests

  • Pulsotonometry
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Where

1 site
IRCCS Policlinico San Donato
San Donato Milanese, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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