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Familial Pancreatic Cancer PROPHilation Program in Italy

RecruitingNAAges 18 Years - 80 YearsAllAssociazione Italiana per lo Studio del Pancreas
NCT05724992 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of the PROPH-ITA Study is to perform genetic testing in family members of pancreatic cancer patients who may have a genetic predisposition. The subjects belong to the Italian Registry of Families At Risk of Pancreatic Cancer (IRFARPC, #NCT04095195). This investigational study will assess the genetic background of subjects with familiarity with pancreatic cancer only. Participants may accept to undergo genetic testing as part of the IRFARPC registry, through a saliva-swab-based 41-gene panel test. Up to 3,000 participants will be enrolled in this study.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Being enrolled on the IRFARPC registry * Having familiarity for pancreatic cancer (according to the IRFARPC criteria, Capurso et al. Dig Liv Dis, 2020) * Willingness to participate in saliva-swab-based genetic testing Exclusion Criteria: \- Already known genetic mutation
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What it tests

  • Saliva swab testing
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Where

1 site
Chirurgia generale e del Pancreas Azienda Ospedaliera Universitaria Integrata
Verona, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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