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Integrated Echocardiography and Chest Ultrasound Assessment of Lung Recruitment in Preterm Infants

RecruitingNAAges 1 Hour - 3 DaysAllAlexandria University
NCT05726578 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The primary aim of this work is to evaluate the role of high frequency oscillatory ventilation (HFOV) in recruitment of lung in preterm newborns 32 to 37 weeks gestational age with moderate to severe respiratory distress. The secondary aim is to evaluate the role of chest ultrasound in monitoring of lung recruitment in comparison to routine chest x ray in those babies. Also cardiac hemodynamics will be assesed using functional echocardiography.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Infants will be enrolled if they are 32 to 37 weeks of gestational age, have respiratory distress (RD) in the first 24 h of life, intubated and have invasive respiratory support using HFOV. Signs of RD are tachypnea (respiratory rate \> 60/min), grunting, nasal flaring, chest retraction, and need of oxygen supplementation or other respiratory support. Exclusion Criteria: 1. Known major congenital anomalies including congenital heart diseases. 2. Fetal hydrops. 3. Babies with congenital heart diseases
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What it tests

  • Lung recruitment
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Where

2 sites
Marwa Mohamed Farag
Alexandria, Egypt
Neonatal Intensive Care Unit (NICU) of Alexandria University Maternity Hospital.
Alexandria, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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