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A Study of the Clinical Efficacy and Safety of 20% Cassia Alata Extract Against Tinea Versicolor

RecruitingPhase 1Ages 18 Years - 89 YearsAllThe University of The West Indies
NCT05730244 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to establish the efficacy of Cassia alata extract as a cream form in treating tinea versicolor (liver spots/shifting clouds). The main questions the study aims to answer are:• Does the use of this extract help resolve tinea versicolor better than no treatment? Does the use of this cream have significant side effects i.e, is it safe? Participants will be asked to treat a designated area while leaving additional areas untreated. 1-2 finger tip units of cream will be applied to the treatment site twice daily at least 8 hours apart. Participants will attend the trial clinic every 4 weeks for 12 weeks.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients aged 18-89 of either sex * Clinical features suggestive of tinea versicolor AND Microscopic confirmation using skin scraping stains with chlorazol black preparation AND/OR Wood's lamp fluorescence * No treatment for versicolor in the preceding 4 weeks * No contraindications to the application of C.alata cream including * No history of allergy to C. alata * No history of preservative allergy Exclusion Criteria: * Age \<18 or \>89 years * Pregnant females * History of hypersensitivity to C. alata or preservative * Treatment within 4 weeks prior to enrollment * Lesions which do not meet the diagnostic criteria of tinea versicolor
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What it tests

  • 20% Cassia alata cream
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Where

1 site
University of the West Indies, Mona
Kingston, Jamaica
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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