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โ† Trials
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Influence of Gut Microbiome in Gallstone Disease

Recruitingn/aAges 18 Years - anyAllEast Kent Hospitals University NHS Foundation Truโ€ฆ
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In plain words

What the trial is, and whether it could suit you

The goal of this prospective observational study is to explore the role of the gut microbiome in patients with gallstone disease. The main question\[s\] it aims to answer are: * if there is a relationship between the gut microbiome and the development of complications associated with gallstone disease (such as pancreatitis and acute cholecystitis) * if there are changes in the gut microbiome following cholecystectomy and the relationship with patient outcomes. Participants will be asked to provide stool samples at fixed time points (recruitment, pre- and post-cholecystectomy if applicable and at 6 months and 3 years. They will also be asked to provide stool samples if they represent to hospital with complications associated with their gallstone disease.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * All adults (age \>18 years of age) patients diagnosed with gallstone disease following confirmatory imaging at an East Kent University Foundation Trust Hospital. Patients of any gender, ethnicity or socio-economic background are eligible as well as pregnant women. Patients undergoing both open and laparoscopic cholecystectomy will be included. Exclusion Criteria: * Patients less than 18 years of age and patients who do not have capacity to consent to involvement in the study.
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What it tests

  • Not listed
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Where

1 site
EKHUFT
Ashford, United Kingdom
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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