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Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients

RecruitingNAAges 10 Years - 21 YearsAllUniversity of Florida
NCT05732779 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

We will conduct a two-group randomized controlled trial to examine the eMocha DOT intervention with pediatric HT recipients.In this population, medication nonadherence remains a primary cause of late acute rejection (LAR) episodes, increased number of hospitalizations, graft failure, and patient mortality. Herein, we propose an innovative approach to promote medication adherence and improve patient and graft outcomes.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Eligible participants are 10-21 years of age * Have received a heart transplant and are followed participating pediatric heart transplant centers * English-speaking or Spanish-speaking * Own a smart-phone or have access to the mobile app through other devices * Are willing to receive information through it * Have a MLVI score of greater than 2.0 over the last year Exclusion Criteria: • Those with cognitive impairments will not be eligible for enrollment due to inability to provide informed assent
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What it tests

  • DOT intervention
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Where

4 sites
University of Miami, Miller School of Medicine
Coral Gables, United States
University of Florida
Gainesville, United States
Joe DiMaggio Children's Hospital
Hollywood, United States
FSU College of Medicine
Tallahassee, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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