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Intensive Cancer Screening After Cryptogenic Stroke

RecruitingNAAges 18 Years - anyAllOttawa Hospital Research Institute
NCT05733416 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The INCOGNITO Pilot Trial is a single centre pilot prospective randomized open-label blinded endpoint (PROBE) trial to assess the feasibility of a full-scale randomized trial to determine whether an occult cancer screening strategy of FDG PET/CT (F-fluorodeoxyglucose positron emission/computed tomography) in addition to usual care increases the number of occult cancers diagnosed after screening compared to usual care cancer screening alone in patients with cryptogenic stroke.

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📋 Eligibility rules (as published)
Inclusion Criteria: * adults ≥18 years * presenting to the Ottawa Hospital Stroke Prevention Clinic or the Ottawa Hospital Neurovascular Unit with a first cryptogenic ischemic stroke after advanced evaluation as per American Heart Association guidelines and Saver approach (maximum 3 months after stroke) * patient or delegate willing and able to provide informed consent. Exclusion Criteria: * contraindications to FDG PET/CT (pregnancy or unable to lie still in bed for 20 minutes) * active cancer or previous cancer diagnosis (other than basal or squamous cell carcinoma of the skin)
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What it tests

  • FDG PET/CT
  • Usual Care
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Where

3 sites
Calgary Foothills Medical Centre
Calgary, Canada
The Ottawa Hospital
Ottawa, Canada
Centre Hospitalier de l'Université de Montréal
Montreal, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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