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Effect of Magnesium Sulphate Pretreatment in Pediatric Abdominal Surgery

RecruitingPhase 2, Phase 3Ages 2 Years - 12 YearsAllAssiut University
NCT05736744 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In this study, the investigators will compare the effect of magnesium sulphate pretreatment on the onset and duration of intense and deep neuromuscular Block of rocuronium versus Cis-Atracurium and on the period of no response to nerve stimulation in children undergoing elective open abdominal surgeries.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age group 2-12 years old 2. Both genders 3. Children who will be scheduled to undergo elective laparoscopic surgeries. 4. Patients with American Society of Anesthesiologist physical status classification of 1 or 2- Exclusion Criteria: 1. Patients who are beyond the selected age group. 2. Patients on medications that interfered with muscle activity. 3. Allergy to medications used in this study. 4. Neuro-muscular diseases. 5. Renal or hepatic impairment. 6. Hypermagnesemia (\>2.5 mmol) or hypomagnesemia (\<1.7 mmol). 7. Parental refusal to participate in the study
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What it tests

  • MgSO4
  • Cis-Atracurium
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Where

2 sites
Pediatric hospital, faculty of medicine, Assiut university
Asyut, Egypt
Pediatric hospital
Asyut, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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