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Improving Tissue Repair After Injury in the Muscle-tendon Interface Muscle Tissue Injury

RecruitingNAAges 18 Years - 35 YearsAllBispebjerg Hospital
NCT05746650 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The study is a 2-week human study where 40 patients who are scheduled to undergo reconstructive knee surgery are randomized to administration of GH or placebo following or without neuromuscular electrical stimulation of hamstring muscles.The overall aim is to determine, the role of muscle connective tissue protein synthesis in muscle injury and repair.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Healthy men and women scheduled to undergo reconstructive knee surgery * BMI 18-35 Exclusion Criteria: * Former or current use of growth hormone or anabolic steroids * Use of corticosteroids in the past 3 months * Use of any medication known to affect muscle or tendon turnover * Former participation in a study using deuterated water * Chronic diseases
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What it tests

  • Electrical stimulation
  • Growth hormone (somatropin)
  • Control (No electrical stimulation, nor growth hormone)
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Where

1 site
Bispebjerg Hospital
Copenhagen, Denmark
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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