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Type 2 Diabetes, Obesity and Cortisol Excess

Recruitingn/aAges 18 Years - 75 YearsAllIstituto Auxologico Italiano
NCT05759637 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The present observational cross-sectional study is aimed to assess: the hidden hypercortisolism (HidHyCo) prevalence in a sample of Type 2 diabetes (T2D) patients and the clinical characteristics more frequently associated with the HidHyCo presence and the HidHyCo prevalence in an adequate sample of obese patients without T2D and the clinical characteristics more frequently associated with the HidHyCo presence.

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📋 Eligibility rules (as published)
Inclusion Criteria: patients with T2D and Obesity Exclusion Criteria: * pregnancy/breast feeding, * sleep apnea, * prepuberal onset of hypertension, hormonal hypersecreting adrenal mass, * symptoms of hypercortisolism; * already known secondary hypertension; * conditions associated with increased hypothalamic-pituitary-adrenal (HPA) axis activity, -severe autoimmune/rheumatologic and hematologic diseases, alcoholism, kidney disease (glomerular filtration rate \<60) * drugs influencing the HPA axis activity. For inclusion in Group 2 the presence of T2D will be an exclusion criteria
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What it tests

  • 1mg DST
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Where

5 sites
Istituto Auxologico Italiano
Milan, Italy
Niguarda Hospital
Milan, Italy
Campus Bio-Medico University
Roma, Italy
University of Siena
Siena, Italy
Azienda Ospedaliero Universitaria, Santa Maria della Misericordia di Udine
Udine, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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