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Intermittent Fasting Versus Carbohydrate Drinks Before Surgery

RecruitingNAAges 18 Years - anyAllAcademisch Medisch Centrum - Universiteit van Ams…
NCT05760339 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to investigate whether time-restricted feeding, a form of intermittent fasting, before surgery improves insulin resistance around the time of surgery, compared to carbohydrate drinks and standard fasting before surgery.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Undergoing elective orthopaedic surgery; * Intermediate, major or complex surgery according to the Surgical Outcome Risk Tool (SORT; http://www.sortsurgery.com/) severity of surgery classification; * Scheduled for surgery at least 17 days from the date of screening; * Motivated to follow a time restricted feeding regimen. * Willing and able to provide written informed consent. Exclusion Criteria: * History of diabetes mellitus; * History of feeding or eating disorders; * History of delayed gastric emptying or gastro-oesophageal reflux * Active malignancy * Patients classified as ASA IV by the attending anaesthetist; * BMI \< 18.5 or ≥ 35; * Outpatient or day case surgery; * Palliative surgery; * Participation in another clinical trial that is interfering with the procedures or outcomes of the PRINCESS trial; * Patients unable to fully comply to study needs (e.g. legally incapable patients or patients unable to communicate in Dutch).
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What it tests

  • Time-restricted feeding
  • Carbohydrate loading
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Where

1 site
Amsterdam UMC location AMC
Amsterdam, Netherlands
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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