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PrEP and MOUD Rapid Access for Persons Who Inject Drugs: The CHORUS+ Study

RecruitingNAAges 18 Years - anyAllBoston Medical Center
NCT05769218 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The US opioid overdose epidemic has been accompanied by an increase in human immunodeficiency (HIV) among persons who inject drugs. HIV pre-exposure prophylaxis (PrEP) is an FDA approved medication taken daily orally by individuals who are HIV negative, but who are at increased risk for HIV. In order to obtain PrEP, a prescription is needed. Before being prescribed HIV PrEP, it is recommended by the Centers for Disease Control and Prevention (CDC) to obtain an HIV test first. Although home HIV self-test kits are recommended by the CDC and are locally available, uptake remains low. CHORUS+ (Comprehensive HIV, Hepatitis C, and Opioid Use Disorder Response to the Unaddressed Syndemic +) is a theory-based, peer-delivered, mobile phone-supported intervention focused on enhancing uptake and adherence to HIV PrEP (primary outcome), and continuation of MOUD (secondary outcome) among persons who

Sign in to get the eligibility rules as simple questions to take to your doctor.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Injected opioids within the past 6 months (by self-report) * Willingness to provide contact information for two family members or friends * Willingness to sign medical records release forms * Ability to speak English * Plans to reside in Boston area for the next 6 months * Are medically cleared to take PrEP and MOUD (normal renal and PrEP-related labs) Exclusion Criteria: * Persons with previous HIV diagnosis (by self-report; confirmed via HIV test result) * Express desire to harm themselves or others * Individuals who are pregnant at baseline * Individuals who are already enrolled in an interventional study
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What it tests

  • CHORUS+
  • Standard of care
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Where

2 sites
Boston Medical Center Faster Paths Bridge Clinic
Boston, United States
Victory Programs Mobile Prevention Services Van and Navigation Center
Boston, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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