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Complete Revascularization Versus Culprit Lesion Only PCI in NSTEMI

RecruitingNAAges 18 Years - anyAllLeipzig Heart Science gGmbH
NCT05786131 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Prospective, randomized, controlled, multicenter, open-label trial to study whether multivessel percutaneous coronary intervention (PCI) is superior over culprit-lesion only PCI in patients with non-ST-segment elevation myocardial infarction (NSTEMI) and multivessel coronary artery disease.

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📋 Eligibility rules (as published)
Inclusion Criteria: * NSTEMI as suggested by high-sensitivity troponin algorithms * Multivessel coronary artery disease * Identifiable culprit lesion * Informed consent Exclusion Criteria: * Age \<18 years * Cardiogenic shock * Sustained ventricular tachycardia (VT) or ventricular fibrillation (VF) * Contraindication for coronary revascularization * Prior coronary artery bypass graft * Indication for coronary artery bypass graft surgery * Non-culprit lesion located in the left main coronary artery * Co-morbidity with life expectancy less than 6 months * Type 2 myocardial infarction * Pregnancy and breast feeding period
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What it tests

  • Culprit-lesion revascularization
  • Non-culprit-lesion revascularization
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Where

58 sites
LKH Univ. Klinikum Graz, Clinical Department of Cardiology
Graz, Austria
Medizinische Universität Innsbruck, Universitätsklinik für Innere Medizin III
Innsbruck, Austria
Klinik Ottakring, 3. medizinische Abteilung
Vienna, Austria
Zentralklinik Bad Berka, Klinik für Kardiologie
Bad Berka, Germany
Universitäts-Herzzentrum Bad Krozingen, Klinik für Kardiologie und Angiologie
Bad Krozingen, Germany
Kerckhoff Klinik
Bad Nauheim, Germany
Herz- und Diabeteszentrum NRW, Universitätsklinikum der Ruhr-Universität Bochum, Klinik für Allgemeine und Interventionelle Kardiologie/Angiologie
Bad Oeynhausen, Germany
BG Klinikum Unfallkrankenhaus Berlin gGmbH, Klinik für Innere Medizin/Kardiologie
Berlin, Germany

…and 50 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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