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Hysteroscopy vs. Endouterine Aspiration in the Management of Trophoblastic Retention

RecruitingNAAges 18 Years - 42 YearsFemaleUniversity Hospital, Montpellier
NCT05789940 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Introduction: Incomplete early miscarriage is defined as early miscarriage with persistent intrauterine material on ultrasound. Intrauterine retention of trophoblastic debris is not an uncommon phenomenon. These retentions may initially be asymptomatic but are often responsible for persistent metrorrhagia and endometritis. This symptomatology often accentuates the psychological distress of patients mourning the pregnancy. Incomplete miscarriages are mainly managed by the gynecological emergency department. The recommendations of the Collège National des Gynécologues et Obstétriciens Français (CNGOF) suggest as a first line of treatment: either surgical management or expectant care. The choice between the two is left to the discretion of the doctor and the patient. there are no clear recommendations as to the choice between hysteroscopy and aspiration. Within the teams, the choice is ofte

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📋 Eligibility rules (as published)
Inclusion Criteria: * Management for trophoblastic retention after early spontaneous miscarriage (\<14 weeks of amenorrhea) * Diagnosis of intrauterine trophoblastic retention by endovaginal pelvic ultrasound * Shared decision for surgical management Exclusion Criteria: * Known uterine malformation * Patient who has received surgical treatment for current intrauterine retention * Patient with an intrauterine device (IUD) * Pregnancy obtained by medically assisted procreation * Indication for emergency surgical management for haemostatic purposes * Failure to obtain free, informed and written consent after a period of reflection * Person not affiliated or beneficiary of a national health insurance system * Person protected by law, under guardianship or curatorship * Person participating in other interventional research involving the human person
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What it tests

  • hysteroscopy
  • Aspiration
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Where

4 sites
CHU de Bordeaux - Hôpital Pellegrin
Bordeaux, France
CHU de Montpellier - Hôpital Arnaud de Villeneuve
Montpellier, France
CHU de Nice - Hôpital Archet II
Nice, France
CHU de Nîmes - Hôpital Carémeau
Nîmes, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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