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Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine for Intermediate Cervical Plexus Block

RecruitingPhase 4Ages 21 Years - 60 YearsAllDamanhour Teaching Hospital
NCT05793060 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

Background: Many thyroidectomy patients suffer from postoperative pain that could delay early hospital discharge and place a significant burden on both the patient and the healthcare team. Bilateral intermediate cervical plexus block (ICPB) provides good analgesia for neck surgery, including thyroidectomy. However, the duration of a single-shot nerve block is usually short. Therefore, adjuvants are used in peripheral nerve blocks. Objectives: To compare the safety and efficacy of dexmedetomidine versus dexamethasone as adjuvants to bupivacaine in ultrasound-guided intermediate cervical plexus block in patients undergoing total thyroidectomy under general anesthesia. Patients and Methods: This is a randomized, double-blind, phase four, prospective clinical trial; carried out on 60 patients, who were candidates for total thyroidectomy under general anesthesia at our hospital. Patients we

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * American Society of Anesthesiologists (ASA) physical status โ‰ค II * Age from 21 to 60 years * Body Mass Index (BMI) โ‰ค 35 kg/m2 Exclusion Criteria: * ASA physical status \> II * Age \< 21 years or \> 50 years * BMI \> 35 kg/m2 * Bronchial asthma * Chronic obstructive pulmonary disease * Restrictive lung diseases * Sick sinus syndrome * Sinus bradycardia * Hypertension * Chronic hypotension * Ischemic heart disease * Coagulopathies * Hepatic insufficiency * Renal insufficiency * Diabetes mellitus * Peripheral neuropathy * Thyroid malignancy * Hyperthyroidism * Substernal goiter * Patients on beta-blockers * Patients using pacemakers * Alcohol or drug abuse * Allergy to the study drugs
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What it tests

  • Dexmedetomidine Hydrochloride
  • Dexamethasone Phosphate
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Where

1 site
Damanhour Teaching Hospital
Damanhลซr, Egypt
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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