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Routine Versus As-Needed Stress Testing in Asymptomatic Patients With High-Risk Coronary Calcium

RecruitingNAAges 19 Years - anyAllSamsung Medical Center
NCT05796739 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of the SMART-EXAM (SMart Angioplasty Research Team-Pragmatic Randomized Trial for Comparing Routine versus As-Needed EXercise or Pharmacologic Stress Testing in Asymptomatic Patients with High-Risk Coronary CalciuM) trial is to compare the major adverse cardiovascular events between routine stress testing and as-needed stress testing in asymptomatic patients with high-risk coronary calcium (Agatston Score ≥ 400) without proven ASCVD.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Subject must be at least 19 years of age. ② Asymptomatic patients with high-risk coronary calcium (Agatston Score ≥ 400) Exclusion Criteria: * Documentation of objective evidence of inducible ischemia before enrollment * Presence of significant coronary artery stenosis (≥ 70% diameter stenosis) confirmed by coronary angiography or coronary computed tomography angiography before enrollment * History of coronary revascularization procedure ④ Pregnancy or breast feeding ⑤ Non-cardiac co-morbid conditions are present with life expectancy \<1 year or that may result in protocol non-compliance (per site investigator's medical judgment) ⑥ Unwillingness or inability to comply with the procedures described in this protocol.
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What it tests

  • Non-invasive stress test
  • Medical treatment without further testing
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Where

1 site
SamsungMedicalCenter
Seoul, South Korea
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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