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OPEN Versus InTact Capsule Proton Pump Inhibitors for the Treatment of Marginal Ulcers

RecruitingPhase 4Ages any - anyAllStephen Firkins
NCT05799105 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to identify the most effective way to take acid-blocking medications to treat stomach ulcers in patients who have undergone gastric bypass surgery. The main questions it aims to answer are: * is taking an acid-blocking medication by opening the capsule and only taking the contents of the capsule (open-capsule) more or less effective than taking the capsule as a whole (intact-capsule) for treating ulcers in patients who have a history of gastric bypass surgery? * does taking the open versus intact medication decrease the number of procedures and complications from untreated ulcers? Participants with ulcers will be instructed to take acid-blocking medications (called proton-pump inhibitors) either by opening the capsule and taking only the contents or by taking the capsule whole. These medications are the gold standard for treatment of stomach ulcers. P

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📋 Eligibility rules (as published)
Inclusion Criteria: * Subjects diagnosed with marginal ulceration post-gastric bypass on upper endoscopy Exclusion Criteria: * Refusal to start PPI medication OR current open-capsule PPI use at the time of diagnosis of the marginal ulcer
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What it tests

  • Omeprazole 40 milligrams
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Where

1 site
Cleveland Clinic Foundation
Cleveland, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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