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Effect of Altitude on Postdural Puncture Headache After Caesarean Delivery

Recruitingn/aAges 18 Years - anyFemaleB.P. Koirala Institute of Health Sciences
NCT05804448 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

The aim of this study is to examine the effects of altitude (high altitude versus low altitude) on incidence and severity of postural puncture headache (PDPH) following spinal anaesthesia for caesarean delivery. The investigators hypothesized that the risk of PDPH would be higher in highlander parturients than in lowlander parturients.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Parturient, aged more than or equal to 18 years * American society of Anesthesiologist 2 and 3 * Scheduled for elective and non-elective (category 2 \& 3) caesarean delivery with spinal anesthesia * Native to their resident altitude i.e., those born, raised, and have continuously lived at the same altitude, at least for the past 1 year. Exclusion Criteria: * Hypertensive disorder * Cerebrovascular disease * Mental disorder (schizophrenia and other psychotic disorders) * Known fetal anomalies * Contraindication to spinal anaesthesia. * Those requiring general anaesthesia for delivery due to failed spinal anesthesia * Major post-delivery complications (severe haemorrhage, sepsis, or ICU admission) * Those who migrate from their resident altitude (either low to high or vice versa) within 7 days post-delivery will also be excluded.
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What it tests

  • Not listed
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Where

2 sites
Karnali Academy of Health Sciences
Jumla, Nepal
BP Koirala Institute of Health Sciences (BPKIHS)
Dharฤn, Nepal
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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