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Investigating Neural Biomarkers for Gait in Parkinson's Patients

Recruitingn/aAges 18 Years - anyAllSwiss Federal Institute of Technology
NCT05820074 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This observational study's main goal is to learn more about the neural mechanisms during movement in Parkinson's disease. Furthermore, it aims to inspire personalised treatment options. Participants will undergo a protocol that involves walking and gait-related motor tasks, such as seated stepping. During the protocol, brain activity will be recorded.

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📋 Eligibility rules (as published)
Inclusion Criteria: All participants * must have given informed consent as documented by signature * agree to comply with the study procedures Healthy control group * no neurological, orthopedic, or rheumatologic disease history * no identified sensory impairment. * no epilepsy and self-diagnosed acute or chronic psychiatric disorders Parkinson's Patients * non-tremor dominant idiopathic PD patients * presence of postural instability (UPDRS \>1 for postural instability \[17\]), gait disturbance, and absence of other causes of reduced balance * Implanted with Percept™ PC neurostimulator * Able to be in the stimulation OFF Exclusion Criteria: * Relevant cognitive impairment, with a score on Montréal Cognitive Assessment (MoCA) \< 20 * History of physical or neurological condition that interferes with study procedures * Social and/or personal circumstances interfering with the ability to come to the session
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What it tests

  • Neural Activity Recording
  • Movement Parameter Recording
  • Neuromodulation
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Where

1 site
Cereneo
Vitznau, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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