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Evaluation of a New Multiplex Quantitative PCR Technique for the Diagnosis of Echinococcosis

RecruitingNAAges 18 Years - anyAllCentre Hospitalier Universitaire de Besancon
NCT05824442 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Echinococcosis is a severe parasitosis caused by the development of the tapeworm larva Echinococcus multilocularis, responsible for alveolar echinococcosis (AE) or Echinococcus granulosus, responsible for cystic echinococcosis (CE). The treatment is based on surgery (only possible in 30 to 40% of cases) and/or on a benzimidazole antiparasitic treatment, especially albendazole. Albendazole is only parasitostatic, it slows down the development of the parasite but does not kill it. It is often prescribed for life. Monitoring the effectiveness of the treatment is therefore necessary, requiring radiological and serological monitoring once or twice a year. Being a chronic disease whose treatment is not always curative, patients quality of life is impacted, with a high level of anxiety described in some patients. The diagnosis, evoked on radiological arguments, is then confirmed by serological

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📋 Eligibility rules (as published)
Inclusion Criteria: * Men and women aged \>18 years with a diagnosis of echinococcosis (Alveolar Echinococcosis or Cystic Echinococcosis) established according to the reference criteria * Signature of the informed consent form indicating that the subject has understood the purpose and the procedures required by the study and that he agrees to participate in the study and to comply with the requirements and restrictions about this study * Affiliation to a French social security scheme or beneficiary of such a scheme. Exclusion Criteria: * Legal incapacity or limited legal capacity * Subject unlikely to cooperate in the study and/or low cooperation anticipated by the investigator * Subject without health insurance * Pregnant woman * Subject being in the period of exclusion from another study or provided by the "national volunteer file".
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What it tests

  • Blood sample for multiplex QPCR technique
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Where

1 site
MILLON
Besançon, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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