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โ† Trials
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HFNC Compared With Facial Mask in Patients With Chest Trauma Patients

RecruitingNAAges 20 Years - 99 YearsAllNational Taiwan University Hospital
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In plain words

What the trial is, and whether it could suit you

Guidelines for noninvasive ventilation (NIV) recommend continuous positive airway pressure in patients with thoracic trauma who remain hypoxic . However, no any suggestion was applied for high flow nasal cannula (HFNC). Therefore, Our aim was to determine whether HFNC reduces intubation in severe trauma-related hypoxemia.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: Patients who have the following condition within 72 hours of chest trauma despite receiving standard nasal cannula oxygen therapy \[โ‰ฅ10 L/min\], are eligible for inclusion. * severe hypoxemic respiratory failure \[Arterial partial pressure of oxygen (PaO2)/fraction of inspired oxygen fraction(FiO2) \<300 mmHg\] * with a respiratory rate \>25 breaths/minute and difficulty breathing, or respiratory distress * PaCO2 of 45 mmHg or higher (if the patient requires emergency surgery with endotracheal intubation and mechanical ventilation, the time of inclusion will be the start of the post-extubation period. (Note: For patients who receive emergency trauma surgery with endotracheal intubation and mechanical ventilation, the time of inclusion assessment will be 72 hours after extubation.) Exclusion Criteria: 1. Patients with a Glasgow Coma Scale less than 8 or severe brain injury. 2. Patients with any contraindications to non-invasive ventilation, including acute gastrointestinal bleeding, upper airway obstruction, or hemodynamic instability. 3. Facial trauma involving skull base fractures, facial bone fractures, or orbital floor fractures. 4. Severe injuries involving the nasal sinuses. 5. Patients with cervical spine injuries. 6. Patients with increased intracranial pressure. 7. Patients with facial, nasal, or airway structural abnormalities or surgery that prevents the use of appropriate nasal cannula. 8. Patients after upper airway surgery. 9. Patients who are unable to clearly express their willingness to sign informed consent.
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What it tests

  • high flow nasal cannula
  • Oxygen mask
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Where

2 sites
Department of Traumatology, National Taiwain University Hospital
Taipei, Taiwan
NTUH Hsin-Chu Branch; NTUH Yun-Lin Branch
Taipei, Taiwan
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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