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โ† Trials
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Revascularization Versus Medical Treatment in Patients With Ischemic Left Ventricular Dysfunction

RecruitingNAAges 19 Years - anyAllSamsung Medical Center
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In plain words

What the trial is, and whether it could suit you

Randomized trial to compare clinical outcomes between revascularization versus medical treatment alone in patients with ischemic cardiomyopathy and left ventricular dysfunction.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Subject must be at least 19 years of age * Patients with stage C heart failure and left ventricular ejection fraction\<40% * Patients with significant coronary artery stenosis (diameter stenosis\>50% with proven inducible myocardial ischemia by invasive physiologic assessment) * Coronary artery disease is amenable for percutaneous coronary intervention (PCI) * Subject is able to verbally confirm understandings of risks, benefits and treatment alternatives of receiving invasive approach and he/she or his/her legally authorized representative provides written informed consent prior to any study related procedure. Exclusion Criteria: * Myocardial infarction by universal definition within 4 weeks of randomization * Non-viable myocardium in myocardial viability test (cardiac magnetic resonance, dobutamine-stress echocardiography, delayed single-photon emission computerized tomography, or aneurysmal change in echocardiography) * Target lesions not amenable for PCI by operators' decision * Patients who need left ventricular assisted device (LVAD) or heart transplantation at the time of randomization * Intolerance to Aspirin, Clopidogrel, Prasugrel, Ticagrelor, Heparin, or Everolimus * Known true anaphylaxis to contrast medium (not allergic reaction but anaphylactic shock) * Pregnancy or breast feeding * Non-cardiac co-morbid conditions are present with life expectancy \<2 year or that may result in protocol non-compliance (per site investigator's medical judgment) * Unwillingness or inability to comply with the procedures described in this protocol.
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What it tests

  • Percutaneous coronary intervention
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Where

1 site
Samsune Medical Center
Seoul, South Korea
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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