🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Measuring Acute Drug Demand in Humans

RecruitingEARLY Phase 1Ages 18 Years - 65 YearsAllUniversity of Maryland, Baltimore
NCT05829655 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

This research is being done to evaluate whether suvorexant may reduce the use of, subjective liking, and demand for various drugs.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Age between 18 and 65 years old * Meets Diagnostic and Statistical Manual-5 criteria for Opioid Use Disorder (OUD) (moderate or severe) * Lifetime substance use history criterion \[blinded\] * Medically cleared to take suvorexant and blinded study medications * Be in good general health based on a physical examination, medical history, vital signs, and screening urine and blood tests Exclusion Criteria: * Pregnant or breast feeding * Seeking opioid use treatment * Significant mental health or physical disorder that is expected to interfere with study participation as assessed by the study physicians or medical staff * Known contraindications or allergies to suvorexant and/or the blinded study medications
💊

What it tests

  • Drug A (Blinded Drug)
  • Drug B (Blinded Drug)
  • Drug C (Blinded Drug)
  • Drug D (Blinded Drug)
  • Suvorexant (20mg/day)
📍

Where

1 site
General Clinical Research Center
Baltimore, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy