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Perineural Methylene Blue Infusion in Lower Limb Amputation Surgery

RecruitingNAAges 18 Years - anyAllTanta University
NCT05830630 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective randomized controlled study will be conducted to evaluate the analgesic effect of continuous perineural infusion of methylene blue with bupivacaine on acute postoperative pain and to evaluate its preventive role against chronic phantom pain in patients undergoing lower limb amputation surgery

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients of both genders, suffering from vascular insufficiency of one or both lower limbs and scheduled for above or below knee amputation under general anesthesia. Exclusion Criteria: * Patients with a history of allergy to local anesthetics. * Patients with allergy to methylene blue. * Anticoagulant use or coagulopathy.
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What it tests

  • Bupivacaine methylene blue
  • bupivacaine saline
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Where

1 site
Tanta University
Tanta, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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