AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Robotic Hemi-Prostatectomy With Urethral Preservation in Low and Intermediate Risk Monolateral Prostate Cancer

RecruitingNAAges 40 Years - anyMaleFondazione del Piemonte per l'Oncologia
💬

In plain words

What the trial is, and whether it could suit you

On the basis of the now consolidated literature and clinical experience of focal therapies, the execution of partial prostatectomy/hemiprostatectomy with robot-assisted laparoscopic technique can be proposed in a well-selected cohort of patients. The hypothesis is that with this technique it is possible to achieve excellent levels of disease control, in terms of positive surgical margins (PSM) and biochemical recurrence of the disease (BCR), against a minimal impact as regards postoperative functional outcomes (continence and sexual power).

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Signature of the informed consent and consent to the use of personal data * Prostate Specific Antigen (PSA) \< 20 ng/mL * Unilateral organ-confined disease on MRI (performed according to ESUR recommendations and reported according to PiRads V.2) or PET-PSMA (performed according to the recommendations of the EANM and reported according to "EANM standardized reporting guidelines v1.0 for PSMA-PET") * Histological diagnosis of acinar-type prostate cancer unilateral on target biopsy and/or standard biopsy with ISUP \< 3 and ipsilateral on imaging investigations * Eastern Cooperative Oncology Group (ECOG) Performance Status 0-1 * Life expectancy ≥ 5 years * Availability of the patient's pre-operative clinical data * Patients must be available to carry out the follow-up visits defined by the protocol * Absence of retroperitoneal, lymph nodal, bone or visceral metastatic lesions * Patients eligible for robot-assisted radical prostatectomy Exclusion Criteria: * Special histotypes of prostate cancer * Patients with PSA \> 20 ng/ml at diagnosis * Impossibility to perform MRI (with pacemakers, claustrophobia…) or PET-PSMA * Previous prostate surgery (TURP, adenomectomy) * Concomitant treatment with other antineoplastic drugs including investigational endocrine therapies * Serious underlying disease or uncontrolled medical condition including active and uncontrolled infections * Patients with dementia or psychiatric illness that limit compliance with study requirements or that could prevent understanding and/or signing the informed consent.
💊

What it tests

  • Robotic hemi-prostatectomy with urethral preservation
📍

Where

1 site
Fondazione del Piemonte per l'Oncologia
Candiolo, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy