🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Rewards for Cannabis Abstinence-study

RecruitingNAAges 16 Years - 22 YearsAllParnassia Addiction Research Centre
NCT05836207 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to investigate the (cost-)effectiveness of contingency management (CM) compared with Cognitive Behavioural Therapy (CBT) for the treatment of cannabis use disorder (CUD) in youth (16-22 years). The main questions it aims to answer are: * What is the efficacy of 12 weeks outpatient CM versus CBT in youths with a CUD, in terms of cannabis abstinence during the intervention period? * What is the long-term efficacy of CM versus CBT at 6- and 12-months follow-up (FU)? * What is the cost-effectiveness of CM versus CBT at 12-months FU from a societal perspective? Study hypotheses are: 1\. CM will result in more cannabis-abstinent days than CBT during the intervention; 2. CM is more effective and cost-effective than CBT at 12 months follow-up. Eligible patients (n=154) will be randomly assigned to either 12 weeks of outpatient CM or CBT. Assessments are co

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Youths (16-22 years) seeking treatment for a primary CUD * Regular cannabis use (≥14 days) in past 4 weeks * Intention to cease cannabis use during intervention * Able and willing to attend the treatment center and submit urine samples under supervision twice-weekly * Informed consent. Exclusion Criteria: * Health contra-indications (e.g., acute psychosis/suicidality) * Insufficient Dutch language.
💊

What it tests

  • Abstinence-focused Contingency Management (CM) - stand alone
  • Standard Outpatient Cognitive Behavioural Therapy (CBT)
📍

Where

5 sites
Jellinek, Stichting Arkin B.V.
Amsterdam, Netherlands
IrisZorg
Arnhem, Netherlands
Antes Youz
Rotterdam, Netherlands
Brijder
The Hague, Netherlands
Novadic-Kentron
Vught, Netherlands
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy