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Association Between Renal Regional Oxygen Saturation Measured by Near-InfraRed Spectroscopy and Postoperative Renal Failure After Lung Transplantation Surgery: A Pilot Study

Recruitingn/aAges 18 Years - anyAllAssistance Publique Hopitaux De Marseille
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In plain words

What the trial is, and whether it could suit you

Complications after lung transplantation are almost ubiquitous, among which postoperative acute renal failure may represent more than 50% of lung transplant patients and require extrarenal purification in 5 to 13% of cases. Multiple factors are associated with postoperative acute renal failure. These factors can be classified into preoperative, intraoperative, and postoperative factors. While some postoperative complications are explained by donor and recipient factors, the literature suggests that certain intraoperative events represent modifiable or avoidable risk factors that could be targeted by therapeutic interventions to reduce the risk of postoperative acute renal failure. Some of these factors (intraoperative hemodynamic instability, significant bleeding or hypoxemia) can generate renal hypoxic aggression, alone or in combination. However, to date, there is no validated tool av

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📋 Eligibility rules (as published)
Inclusion Criteria: * patient undergoing a lung transplant (mono or bi-transplantation) * Age \>= 18 years * Affiliated to the French social security system Exclusion Criteria: * Renal anatomical abnormality likely to induce a misleading NIRS signal: single kidney, polycystic kidney disease. * Expression of opposition to participation in the research protocol. * Hyperbilurbinemia \> 17mmol/l * Preoperative Extra Corporeal Membran Oxygenation (ECMO). * Preoperative mechanical ventilation
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What it tests

  • Not listed
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Where

1 site
Service d'anesthésie et réanimation adulte
Marseille, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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